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陈辉

陈辉,男,博士,教授,博士生导师。2011年在华南理工大学获工学博士学位(硕博连读)。20117月至20192月在中国科学院水生生物研究所从事藻类生物学与光合逆境响应的研究工作。20193月,入选河南大学黄河学者特聘教授。在Mol Plant, Biol Rev, Biotechnol Biofuel, Appl Energ, Environ Sci Technol等国际著名学术期刊发表论文20余篇,承担国家、省部级科研项目10余项。


研究方向:微藻光合逆境响应、合成生物学及环境应用

光合逆境响应研究方面,关注环境胁迫条件下微藻基于光雷火体育合作用的能量、物质与信号的交互机制与雷火体育适应策略;合成生物学研究方面,聚焦在光合模式蓝藻等底盘细胞中实现基于合成生物学的从CO2到目标天然产物的绿色生物制造;环境应用方面,涉及能源微藻用于环境污染物生物减排、污染物资源化和微藻生物雷火体育的基础理论与生产工艺。

Emailchenhui0010@vip.populardrinkrecipes.com


代表性研究论文:

1. Zheng, Y., C. Xue, H. Chen, A. Jia, L. Zhao, J. Zhang, L. Zhang, and Q. Wang, Reconstitution and expression of mcy gene cluster in the model cyanobacterium Synechococcus 7942 reveals a roll of MC-LR in cell division. New Phytol, 2023. n/a(n/a).

2. Dai, Na, Qiang Wang, Baisheng Xu, and Hui Chen, Remarkable Natural Biological Resource of Algae for Medical Applications. Frontiers in Marine Science, 2022. 9.

3. Chen, H. and Q. Wang, Microalgae-Based Green Bio-ManufacturingHow Far From Us. Frontiers in Microbiology, 2022. 13.

4. Chen H., Li K., Xue C., Wang Q. A Novel Method for Non-invasive Estimation of Primary Productivity in Aquatic Ecosystems Using a Chlorophyll Fluorescence-Induced Dynamic Curve [J]. Frontiers in Microbiology, 2021, 12: 682250.

5. Chen H., Wang Q. Regulatory mechanisms of lipid biosynthesis in microalgae [J]. Biological Reviews, 2021, 96(5): 2373-2391.

6. Chen, H., Wang, X., and Wang, Q. (2020). Microalgal biofuels in China: The past, progress and prospects. Global Change Biology Bioenergy. 12: 1044-1065;

7. Chen, H., and Wang, Q. (2020). Microalgae-based nitrogen bioremediation. Algal Research, 46:101775;

8. Zhang, X., Chen, H., Wang, H., Wang, Q. Time-course effects of Tris(1,3-dichloro-2-propyl) phosphate (TDCPP) on Chlorella pyrenoidosa: Growth inhibition and adaptability mechanisms. Journal of Hazardous Materials, 2021, 402: 123784.

9. Chen, H., Li, T., and Wang, Q. (2019). Ten years of algal biofuel and bioproducts: gains and pains. Planta 249:195-219

10. Chen, H., Wang, J., Zheng, Y., Zhan, J., He, C., and Wang, Q. (2018). Algal biofuel production coupled bioremediation of biomass power plant wastes based on Chlorella sp. C2 cultivation. Applied Energy 211, 296-305

11. Chen, H., and Wang, Q. (2018). Ten years of microalgal biofuels in environmental applications. Science Foundation in China 26(3), 69-80

12. Chen, H., Zheng, Y., Zhan, J., He, C., and Wang, Q. (2017). Comparative metabolic profiling of the lipid-producing green microalga Chlorella reveals that nitrogen and carbon metabolic pathways contribute to lipid metabolism. Biotechnol Biofuels 10(1), 153

13. Chen, H., Zhou, W., Chen, W., Xie, W., Jiang, L., Liang, Q., Huang, M., Wu, Z. and Wang, Q. (2017). Simplified, rapid, and inexpensive estimation of water primary productivity based on chlorophyll fluorescence parameter Fo. J Plant Physiol 211, 128-135

14. Chen, H., Qiu, T., Rong, J.F., He, C.L., and Wang, Q. (2015). Microalgal biofuel revisited: An informatics-based analysis of developments to date and future prospects. Applied Energy 155, 585-598

15. Chen, H., Hu, J., Qiao, Y., Chen, W., Rong, J., Zhang, Y., He, C. and Wang, Q. (2015). Ca2+-regulated cyclic electron flow supplies ATP for nitrogen starvation-induced lipid biosynthesis in green alga. Sci Rep 5, 15117

16. Chen, H., Zhang, Y., He, C., and Wang, Q. (2014). Ca2+ signal transduction related to neutral lipid synthesis in an oil-producing green alga Chlorella sp. C2. Plant Cell Physiol 55(3), 634-644

17. Zhang, Y.M., Chen, H., He, C.L., and Wang, Q. (2013). Nitrogen starvation induced oxidative stress in an oil-producing green alga Chlorella sorokiniana C3. PLoS One 8(7), e69225

18. Ma, F., Zhang, X., Zhu, X., Li, T., Zhan, J., Chen, H., He, C. and Wang, Q. (2017). Dynamic Changes of IsiA-Containing Complexes during Long-Term Iron Deficiency in Synechocystis sp. PCC 6803. Mol Plant 10(1), 143-154

19. Chen, W., Zhang, S., Rong, J., Li, X., Chen, H., He, C., and Wang, Q. (2016). Effective Biological DeNOx of Industrial Flue Gas by the Mixotrophic Cultivation of an Oil-Producing Green Alga Chlorella sp. C2. Environ Sci Technol 50(3), 1620-1627

20. Zhang, X., Chen, H., Chen, W., Qiao, Y., He, C., and Wang, Q. (2014). Evaluation of an oil-producing green alga Chlorella sp. C2 for biological DeNOx of industrial flue gases. Environ Sci Technol 48(17), 10497-10504


承担项目:

1. 国家重点研发计划“合成生物学”重点专项,微藻物质代谢调控网络解析 研究微藻物质代谢调控网络解析,2021-2026,经费总额80万元,主持;

2. 河南省自然科学基金优秀青年基金项目,微藻脂质代谢调控机制,2021-202325万元,主持;

3. 国家重点研发计划合成生物学重点专项子课题,蓝藻环肽毒素合成相关功能基因模块的鉴定及功能研究,2019-2024234万元,主持;

4. 国家自然科学基金面上项目,微藻油脂合成碳同化的关键节点柠檬酸合成酶的Ca2+信号调控机制研究,2019-2022,直接经费59万元,主持;

5. 973计划子课题,能源微藻优良藻种的遗传改造,2011-201550万元,主持;

6. 国家自然科学基金青年基金项目,Ca2+信号转导对小球藻中性脂积累的调控机制,2014-201625万元,主持;

7. 中国科学院水生生物研究所青年人才专项,缺氮胁迫下小球藻Ca2+信号转导对中性脂合成的调控机制,2014-20158万元,主持;

8. 国家自然科学基金重大研究计划项目,雪藻驱动极地碳循环及雷火体育适应低温和高辐射的机制,2019-2022,直接经费290万元,参加;

9. 国家自然科学基金面上项目,蓝细菌Synechocystic sp. PCC 6803 非编码反义RNA ThfR的功能及其调控机制,2018-2021,直接经费65万元,参加;

10. 国家自然科学基金面上项目,长链非编码RNA-HOTAIR的蛋白调控网络的构建及功能研究,2014-201780万元,参加;

11. 国家自然科学基金面上项目,Synechocystis PCC 6803 缺铁诱导蛋白IsiA 相互作用网络的构建及其功能研究,2013-201680万元,参加;

12. 湖北省自然科学基金创新群体项目,微藻固炭脱硝机理及高附加值产物的提取工艺,2017-202050万元,参加;

13. 湖北省自然科学基金重点项目,能源微藻用于去除工业烟气中氮氧化物(NOx)的研究,2013-201510万元,参加。


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